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Glow trial demonstrated enhanced pfs and os with zolbetuximab and capox versus placebo, confirming its efficacy The glow clinical trial showed that zolbetuximab plus capecitabine plus oxaliplatin (capox) significantly prolonged these patients' overall survival (os) and. The fda approved zolbetuximab plus chemotherapy.

The glow trial also confirmed efficacy, with median os improving from 12.16 months to 14.39 months (hr, 0.771 The glow and spotlight studies are a part of astellas' gastric cancer development program to investigate targeted treatment options such as zolbetuximab and. Zolbetuximab's targeted action, combined with.

Zolbetuximab is a novel monoclonal antibody targeting cldn18.2, a protein expressed in gastric mucosa

Zolbetuximab improved both pfs and os when added to. The zolbetuximab approval was supported by data from the phase 3 spotlight trial (nct03504397) and the phase 3 glow trial (nct03653507), in which investigators.

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