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Overview monoclonal gammopathy of undetermined significance (mgus) is a condition in which an atypical protein is found in the blood Myeloma (a cancer of blood cells called plasma cells) lymphoma (a cancer of blood cells called lymphocytes) The protein is called monoclonal protein or m protein

Monoclonal gammopathy of undetermined significance occurs most often in older men. Although mgus is not a cancer, people with it have a slightly higher risk of developing Monoclonal gammopathies are conditions in which abnormal proteins (antibodies) are found in the blood

These proteins are made from a small number of plasma cells in the bone marrow

The most common condition linked with these abnormal proteins is monoclonal gammopathy of undetermined significance. Monoclonal gammopathy of undetermined significance (mgus) happens when abnormal white blood cells make abnormal proteins called m proteins M proteins don’t usually cause issues Most people with mgus don’t have symptoms

But a small percentage of people with this condition may develop blood cancer or a more serious blood disorder. Its presence is often discovered incidentally during blood tests for other conditions Finding a monoclonal protein is a laboratory result, not a disease in itself, but it prompts further evaluation to understand its significance for an. Monoclonal gammopathy refers to the presence of an atypical monoclonal protein (m protein) in the blood

Learn more about the condition here.

Rarely, monoclonal gammopathy can cause symptoms in the absence of malignant disease, which is called monoclonal gammopathy of clinical significance (mgcs). Serum monoclonal proteins are an indicator of abnormal plasma cell proliferation This article explores the diagnostic and prognostic significance of these proteins in various diseases. Mgus stands for monoclonal gammopathy of unknown significance

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